Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3642705 | 0.79 | KMT2A (0.38) | MEN1CYP3A4KMT2AKDM4EMAPT | |
| SCHEMBL16490936 | 0.79 | HSD17B10 (0.39) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL17825685 | 0.79 | POLB (0.36) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL15353466 | 0.75 | CA12 (0.41) | MEN1CYP3A4KMT2ATSHRALDH1A1 | |
| SCHEMBL14454136 | 0.74 | CES2 (0.48) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL22548778 | 0.74 | MAPT (0.34) | KDM4EMAPTHDAC1HDAC6TDP1 | |
| SCHEMBL9720595 | 0.71 | KMT2A (0.47) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL23658405 | 0.70 | POLB (0.30) | — | |
| SCHEMBL13181078 | 0.70 | CES2 (0.48) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL1275288 | 0.70 | GSK3B (0.39) | CYP3A4KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973751-A1 | PHENYL-AMINO-SULFONYL-UREA DERIVATIVES AS FUNGICIDES AND PESTICIDES | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998038172-A1 | PHENYL-AMINO-SULFONYL-UREA DERIVATIVES AS FUNGICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-03 | — | — | WO | disclosed |