Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670224 | 0.80 | SCN1A (0.42) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL12227917 | 0.80 | SCN1A (0.42) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL127629 | 0.79 | IDO1 (0.46) | LMNAKDM4EADRA2ACHRM2ADRA1A | |
| Hydrochloric Acid SCHEMBL28591682 | 0.79 | KDM4E (0.52) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL19984489 | 0.78 | SLC6A4 (0.44) | ADRA2CADRA2AALDH1A1ADRA1ATSHR | |
| SCHEMBL11835643 | 0.78 | TSHR (0.48) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL8775673 | 0.77 | LMNA (0.43) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL9619659 | 0.77 | LMNA (0.43) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| Water SCHEMBL11878861 | 0.76 | IDO1 (0.44) | LMNAKDM4EADRA2ACHRM2ADRA1A | |
| Ammonia Solution, Strong SCHEMBL7282272 | 0.76 | IDO1 (0.44) | LMNAKDM4EADRA2ACHRM2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983222-A1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORPORATION (CA) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052898-A9 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 1999-04-01 | — | — | WO | disclosed |
| WO-1998052898-A1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORPORATION (CA) | 1998-11-26 | — | — | WO | disclosed |
| EP-0613880-A1 | Agent and method for the immunological determination of Diphenhydramine and its metabolites | MERCK PATENT GmbH (DE) | 1994-09-07 | — | — | EP | disclosed |