Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107091 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL8112307 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8107086 | 0.99 | SLC6A2 (0.48) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8106499 | 0.99 | SLC6A2 (0.48) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8106498 | 0.99 | SLC6A2 (0.48) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8106991 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL8097325 | 0.80 | SLC22A1 (0.51) | SLC6A2SLC6A4SIGMAR1HTR2C | |
| SCHEMBL8097321 | 0.80 | SLC22A1 (0.51) | SLC6A2SLC6A4SIGMAR1HTR2C | |
| Hydrochloric Acid SCHEMBL8097372 | 0.78 | CHRM2 (0.45) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8107066 | 0.78 | CHRM2 (0.45) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |