Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123987 | 0.88 | HSD11B1 (0.49) | HSD11B1CNR2 | |
| SCHEMBL8111101 | 0.84 | CNR2 (0.48) | CCR1GAACNR1CNR2 | |
| SCHEMBL13766721 | 0.82 | HSD11B1 (0.52) | HSD11B1CNR1CNR2 | |
| SCHEMBL8416952 | 0.79 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL8111487 | 0.75 | CNR2 (0.55) | GAACNR1CNR2 | |
| SCHEMBL8130522 | 0.74 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL13766700 | 0.73 | HSD11B1 (0.53) | HSD11B1CNR1CNR2 | |
| SCHEMBL13766959 | 0.72 | HSD11B1 (0.50) | HSD11B1 | |
| SCHEMBL13766924 | 0.72 | HTT (0.54) | HSD11B1CNR2 | |
| SCHEMBL13766705 | 0.71 | EPHX2 (0.47) | HSD11B1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979228-A4 | NOVEL CANNABINOID RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0979228-A1 | NOVEL CANNABINOID RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-16 | — | — | EP | disclosed |
| US-5948777-A | ANTIINFLAMMATORY AGENT | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1998041519-A1 | NOVEL CANNABINOID RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-24 | — | — | WO | disclosed |