SCHEMBL8107176

SCHEMBL8107176

CC(=O)CN[C@@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCCCC[C@H](NCC(C)=O)C(N)=O)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.48
▸ ALB P02768 3/20 0.41
▸ TSHR P16473 1/20 0.37
▸ EPOR P19235 1/20 0.34
▸ CCKAR P32238 3/20 0.34
▸ CCKBR P32239 3/20 0.34
▸ SIRT5 Q9NXA8 2/20 0.34
▸ FOLH1 Q04609 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14500495 0.93 ALB (0.43) GLP1RALBTSHREPORSIRT5
SCHEMBL8122831 0.93 GLP1R (0.48) GLP1RALBEPORCCKARCCKBR
SCHEMBL12743650 0.93 GLP1R (0.48) GLP1RALBEPORCCKARCCKBR
SCHEMBL14500436 0.90 GLP1R (0.48) GLP1RALBCCKARCCKBRSIRT5
SCHEMBL14500437 0.90 GLP1R (0.48) GLP1RALBCCKARCCKBRSIRT5
SCHEMBL8115335 0.89 GLP1R (0.56) GLP1RCCKARCCKBR
SCHEMBL14500432 0.89 GLP1R (0.56) GLP1RCCKARCCKBR
SCHEMBL12743531 0.88 GLP1R (0.48) GLP1RALBTSHREPORFOLH1
SCHEMBL8115663 0.87 GLP1R (0.51) GLP1RALBTSHREPORCCKAR
SCHEMBL17369669 0.86 GLP1R (0.55) GLP1RALBCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7261876-B2 Multivalent constructs for therapeutic and diagnostic applications BRACCO INTERNATIONAL BV (NL) 2007-08-28 — — US disclosed
US-7211240-B2 Multivalent constructs for therapeutic and diagnostic applications BRACCO INTERNATIONAL B.V. (NL) 2007-05-01 — — US disclosed
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders ARBOGAST CHRISTOPHE (FR) 2004-10-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders MKI67, TP53, VHL GLP1R 4619/4885ALB 1656/4885TSHR 4153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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