SCHEMBL8122831

SCHEMBL8122831

CC(=O)CN[C@@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCC(=O)NCCCC[C@H](N)C(=O)NCCCC[C@H](NCC(C)=O)C(N)=O)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.48
▸ DPP7 Q9UHL4 2/20 0.38
▸ ALB P02768 1/20 0.37
▸ NOD1 Q9Y239 2/20 0.37
▸ GNAI3 P08754 1/20 0.37
▸ GNAO1 P09471 1/20 0.37
▸ GNAI1 P63096 1/20 0.37
▸ CD40 P25942 1/20 0.35
▸ EPOR P19235 1/20 0.35
▸ RRM1 P23921 1/20 0.33
▸ CCKAR P32238 1/20 0.33
▸ CCKBR P32239 1/20 0.33
▸ FNTA P49354 1/20 0.32
▸ FNTB P49356 1/20 0.32
▸ PGGT1B P53609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12743650 1.00 GLP1R (0.48) GLP1RDPP7ALBNOD1GNAI3
SCHEMBL8107176 0.93 GLP1R (0.48) GLP1RALBEPORCCKARCCKBR
SCHEMBL8116035 0.89 GLP1R (0.50) GLP1RDPP7ALBNOD1GNAI3
SCHEMBL14500432 0.87 GLP1R (0.56) GLP1RCCKARCCKBR
SCHEMBL8115335 0.87 GLP1R (0.56) GLP1RCCKARCCKBR
SCHEMBL14500495 0.86 ALB (0.43) GLP1RALBNOD1EPOR
SCHEMBL14500437 0.86 GLP1R (0.48) GLP1RALBCCKARCCKBR
SCHEMBL14500436 0.86 GLP1R (0.48) GLP1RALBCCKARCCKBR
SCHEMBL12147636 0.85 GLP1R (0.47) GLP1RDPP7NOD1GNAI3GNAO1
SCHEMBL14500475 0.84 GLP1R (0.53) GLP1RALBCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150374843-A1 MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS BRACCO INTERNATIONAL B.V. (NL) 2015-12-31 — — US disclosed
US-20110070165-A1 MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS BRACCO SUISSE SA (CH) 2011-03-24 — — US disclosed
US-7910088-B2 Multivalent constructs for therapeutic and diagnostic applications BRACCO SUISSE SA (CH) 2011-03-22 — — US disclosed
US-7211240-B2 Multivalent constructs for therapeutic and diagnostic applications BRACCO INTERNATIONAL B.V. (NL) 2007-05-01 — — US disclosed
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders ARBOGAST CHRISTOPHE (FR) 2004-10-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110070165-A1 MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS CD47, BCR, CD44 GLP1R 2595/4885DPP7 1750/4885ALB 589/4885
US-20150374843-A1 MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS CD47, BCR, CD44 GLP1R 2595/4885DPP7 1750/4885ALB 589/4885
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders MKI67, TP53, VHL GLP1R 4619/4885DPP7 3202/4885ALB 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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