Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990005 | 0.82 | NR1H2 (0.33) | NR1H2GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL1268620 | 0.82 | NR1H2 (0.33) | NR1H2GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL15519998 | 0.81 | PPM1D (0.35) | NR1H2ABCB1 | |
| SCHEMBL28566941 | 0.81 | STS (0.38) | NR1H2GPR119NR1H3 | |
| SCHEMBL24070869 | 0.80 | CHRM2 (0.35) | NR1H2GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL9597063 | 0.80 | GBA2 (0.34) | — | |
| SCHEMBL15288943 | 0.79 | CHRM2 (0.37) | NR1H2GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL5160617 | 0.75 | NR1H2 (0.34) | NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL28563885 | 0.74 | STS (0.39) | NR1H2NR1H3 | |
| SCHEMBL2059317 | 0.74 | CYP2D6 (0.39) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |