Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12248003 | 0.80 | TSHR (0.38) | TSHR | |
| SCHEMBL16363530 | 0.80 | TDP1 (0.33) | TSHRTDP1 | |
| SCHEMBL34254 | 0.80 | TDP1 (0.33) | TSHRTDP1 | |
| SCHEMBL777881 | 0.80 | TDP1 (0.33) | TSHRTDP1 | |
| SCHEMBL11760283 | 0.76 | TAAR1 (0.31) | TDP1 | |
| SCHEMBL778395 | 0.76 | TDP1 (0.31) | TDP1 | |
| SCHEMBL6911929 | 0.74 | MIF (0.38) | — | |
| SCHEMBL3977898 | 0.74 | TSHR (0.44) | TSHR | |
| SCHEMBL11758712 | 0.73 | MAP2K7 (0.31) | — | |
| SCHEMBL14094187 | 0.73 | LMNA (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043675-A1 | 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-02 | — | — | WO | disclosed |
| EP-0523125-A1 | NOVEL PIPERIDIN-4-SPIRO-OXIRANES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1993-01-20 | — | — | EP | disclosed |
| WO-1991015492-A1 | NOVEL PIPERIDIN-4-SPIRO-OXIRANES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1991-10-17 | — | — | WO | disclosed |