Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8107905 | 0.87 | LTA4H (0.58) | LTA4HACHE | |
| SCHEMBL8111775 | 0.87 | LTA4H (0.58) | LTA4H | |
| Water SCHEMBL8106357 | 0.87 | LTA4H (0.58) | LTA4HACHE | |
| SCHEMBL2107118 | 0.86 | LTA4H (1.00) | LTA4H | |
| SCHEMBL3494091 | 0.85 | LTA4H (1.00) | LTA4H | |
| SCHEMBL8107892 | 0.83 | LTA4H (0.76) | LTA4H | |
| SCHEMBL8112098 | 0.77 | LTA4H (0.65) | LTA4HACHE | |
| SCHEMBL2108981 | 0.76 | LTA4H (1.00) | LTA4HACHE | |
| SCHEMBL3494088 | 0.76 | LTA4H (0.72) | LTA4HACHE | |
| Hydrochloric Acid SCHEMBL8113562 | 0.76 | LTA4H (0.63) | LTA4HACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162823-A | LTA4 hydrolase inhibitors | G.D. SEARLE & CO. (US) | 2000-12-19 | — | — | US | claimed |
| WO-1998040354-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-09-17 | — | — | WO | claimed |
| US-6162823-A | LTA4 hydrolase inhibitors | G.D. SEARLE & CO. (US) | 2000-12-19 | — | — | US | disclosed |
| WO-1998040354-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-09-17 | — | — | WO | disclosed |