Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11852932 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1CDC25BTDP1 | |
| SCHEMBL1200459 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1CDC25BTDP1 | |
| SCHEMBL11613274 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1CDC25BTDP1 | |
| SCHEMBL22146619 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1CDC25BTDP1 | |
| SCHEMBL13680173 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1CDC25BTDP1 | |
| SCHEMBL21664378 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1CDC25BTDP1 | |
| SCHEMBL20109819 | 0.79 | CDC25B (0.54) | ALDH1A1MAPK1L3MBTL1CDC25BTDP1 | |
| SCHEMBL3041849 | 0.79 | CDC25B (0.65) | ALDH1A1MAPK1L3MBTL1CDC25BTDP1 | |
| SCHEMBL2679263 | 0.78 | CDC25B (0.52) | ALDH1A1MAPK1L3MBTL1CDC25BKMT2A | |
| SCHEMBL2679262 | 0.78 | CDC25B (0.52) | ALDH1A1MAPK1L3MBTL1CDC25BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632036-B1 | Amide derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses | SANKYO CO (JP) | 2000-03-01 | — | — | EP | disclosed |
| US-5614550-A | ANTICHOLESTEROL AGENTS OR ARTERIOSCLEROSIS AGENTS FOR HUMANS | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5534529-A | Substituted aromatic amides and ureas derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0632036-A2 | Amide and urea derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1995-01-04 | — | — | EP | disclosed |