Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107529 | 1.00 | MEN1 (0.33) | MEN1ALDH1A1MAPTKMT2ACTSK | |
| SCHEMBL8107527 | 1.00 | MEN1 (0.33) | MEN1ALDH1A1MAPTKMT2ACTSK | |
| Water SCHEMBL8098440 | 0.87 | NR1H2 (0.34) | MEN1KMT2ANR1H2 | |
| SCHEMBL8107979 | 0.86 | NR1H2 (0.36) | MEN1ALDH1A1KMT2ANR1H2 | |
| SCHEMBL9595771 | 0.86 | NR1H2 (0.36) | MEN1ALDH1A1KMT2ANR1H2 | |
| SCHEMBL8106571 | 0.85 | NR1H2 (0.35) | MEN1KMT2ANR1H2 | |
| SCHEMBL8112404 | 0.85 | NR1H2 (0.35) | MEN1KMT2ANR1H2 | |
| SCHEMBL9595653 | 0.85 | NR1H2 (0.35) | MEN1KMT2ANR1H2 | |
| SCHEMBL8108016 | 0.84 | NR1H2 (0.32) | MEN1KMT2ANR1H2 | |
| SCHEMBL8098400 | 0.83 | NR1H2 (0.32) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |