Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.67 |
| ▸ | CTSK | P43235 | 7/20 | 0.67 |
| ▸ | CTSB | P07858 | 3/20 | 0.67 |
| ▸ | CTSL | P07711 | 2/20 | 0.67 |
| ▸ | AKT1 | P31749 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.62 |
| ▸ | PTPRA | P18433 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16909161 | 1.00 | CTSS (0.67) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL8107395 | 1.00 | CTSS (0.67) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL16909159 | 1.00 | CTSS (0.67) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL16909172 | 0.95 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL16909174 | 0.95 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2404125 | 0.94 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2447627 | 0.94 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2406384 | 0.94 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2444606 | 0.94 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2405030 | 0.94 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084112-A | Method for preparing ω-aminoalkanoic acid derivatives from cycloalkanones | EMISPHERE TECHNOLOGIES, INC. (US) | 2000-07-04 | — | — | US | disclosed |