Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.57 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091847 | 0.87 | CYP2C9 (0.59) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL14472045 | 0.83 | HTT (0.63) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL1821479 | 0.83 | PTGS1 (0.74) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL1821480 | 0.83 | PTGS1 (0.74) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL11674974 | 0.82 | GABBR2 (0.63) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL20629917 | 0.82 | GABBR2 (0.63) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL11674975 | 0.82 | GABBR2 (0.63) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL11141872 | 0.81 | HTT (0.61) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL85764 | 0.79 | GABBR2 (0.66) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL10448945 | 0.79 | HTT (0.59) | HTTCA2CA1GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780492-A | Concentrated solutions of U.V. stabilizers | SANDOZ LTD. (CH) | 1988-10-25 | — | — | US | claimed |
| US-4774332-A | LIGHT STABILIZERS FOR POLYMERS | SANDOZ, LTD. (CH) | 1988-09-27 | — | — | US | claimed |
| US-6046261-A | STABILIZER FOR ORGANIC MATERIAL HAVING EXCELLENT BLOOMING RESISTANCE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0498620-B1 | Colored polyacetal resin composition | POLYPLASTICS CO (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5397821-A | Light and heat stabilizers, low volatility | ELFATOCHEM NORTH AMERICA, INC. (US) | 1995-03-14 | — | — | US | disclosed |
| US-5338853-A | N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-08-16 | — | — | US | disclosed |
| US-5212222-A | Nitrogen compound, fatty ester, salt, hindered phenol | POLYPLASTICS CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0498620-A1 | Colored polyacetal resin composition | POLYPLASTICS CO. LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| EP-0434080-A1 | Derivatives of N-hals-substituted amic acid hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4780492-A | Concentrated solutions of U.V. stabilizers | SANDOZ LTD. (CH) | 1988-10-25 | — | — | US | disclosed |
| US-4774332-A | LIGHT STABILIZERS FOR POLYMERS | SANDOZ, LTD. (CH) | 1988-09-27 | — | — | US | disclosed |
| US-4247694-A | PHOTOSTABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |