Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.72 |
| ▸ | MMP10 | P09238 | 8/20 | 0.72 |
| ▸ | MMP8 | P22894 | 8/20 | 0.72 |
| ▸ | MMP2 | P08253 | 1/20 | 0.64 |
| ▸ | MMP3 | P08254 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934527 | 0.88 | MMP13 (0.82) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL8109228 | 0.88 | MMP13 (0.72) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL4926424 | 0.87 | MMP13 (0.70) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL942396 | 0.86 | MMP13 (0.61) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL4935921 | 0.86 | MMP13 (0.78) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL944678 | 0.86 | MMP13 (0.61) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL942256 | 0.86 | MMP13 (0.59) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL943883 | 0.86 | MMP13 (0.59) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL941833 | 0.85 | MMP13 (0.58) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL943314 | 0.85 | MMP13 (0.57) | MMP13MMP10MMP8MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149191-A1 | HETERO BICYCLIC CARBOXAMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2008-12-11 | — | — | WO | disclosed |