SCHEMBL8108006

SCHEMBL8108006

CCC(C)(C)c1ccc(OCC(=O)Nc2cc(Cl)[c]c(Cl)c2)c(C(C)(C)CC)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.57
KMT2A Q03164 7/20 0.57
NPSR1 Q6W5P4 6/20 0.57
MAPK1 P28482 6/20 0.57
SMN1; SMN2 Q16637 5/20 0.57
ALDH1A1 P00352 1/20 0.57
MAPT P10636 4/20 0.43
HTT P42858 3/20 0.43
UBE2N P61088 2/20 0.43
GLA P06280 1/20 0.43
MITF O75030 1/20 0.43
TRPV1 Q8NER1 1/20 0.42
NAMPT P43490 1/20 0.41
RAD52 P43351 2/20 0.39
STAT3 P40763 1/20 0.39
RCE1 Q9Y256 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
RAB9A P51151 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11287066 0.87 MEN1 (0.59) MEN1KMT2ANPSR1MAPK1SMN1; SMN2
SCHEMBL10601000 0.86 MEN1 (0.54) MEN1KMT2ANPSR1MAPK1SMN1; SMN2
SCHEMBL10738515 0.85 MEN1 (0.60) MEN1KMT2ANPSR1MAPK1SMN1; SMN2
SCHEMBL9340133 0.84 SMN1; SMN2 (0.61) MEN1KMT2ANPSR1MAPK1SMN1; SMN2
SCHEMBL30654944 0.82 KMT2A (0.54) MEN1KMT2ANPSR1MAPK1SMN1; SMN2
SCHEMBL29120901 0.82 KMT2A (0.54) MEN1KMT2ANPSR1MAPK1SMN1; SMN2
SCHEMBL11851291 0.81 MEN1 (0.58) MEN1KMT2ANPSR1MAPK1SMN1; SMN2
SCHEMBL7208905 0.81 NPSR1 (0.55) MEN1KMT2ANPSR1MAPK1SMN1; SMN2
SCHEMBL11002253 0.80 NPSR1 (0.43) MEN1KMT2ANPSR1MAPK1SMN1; SMN2
SCHEMBL13081865 0.80 SMN1; SMN2 (0.68) MEN1KMT2ANPSR1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6156489-A Silver halide photosensitive material KONICA CORPORATION (JP) 2000-12-05 US disclosed
EP-0651289-B1 Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging EASTMAN KODAK CO (US) 1999-08-11 EP disclosed
US-5482821-A Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1996-01-09 US disclosed
EP-0651289-A1 Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging EASTMAN KODAK COMPANY (US) 1995-05-03 EP disclosed
EP-0646841-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0152296-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1988-08-24 EP disclosed
US-4600688-A MAGENTA COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-07-15 US disclosed
EP-0152296-A2 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1985-08-21 EP disclosed