SCHEMBL7208905

SCHEMBL7208905

CCC(C)(C)c1ccc(OCC(=O)Nc2c[c]ccc2)c(C(C)(C)CC)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 6/20 0.55
SMN1; SMN2 Q16637 6/20 0.55
MEN1 O00255 5/20 0.55
KMT2A Q03164 5/20 0.55
MAPK1 P28482 5/20 0.55
ALDH1A1 P00352 1/20 0.55
MAPT P10636 5/20 0.43
HTT P42858 4/20 0.43
UBE2N P61088 2/20 0.43
MITF O75030 2/20 0.43
NAMPT P43490 1/20 0.42
GLA P06280 1/20 0.41
NOTUM Q6P988 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
RAD52 P43351 2/20 0.40
STAT3 P40763 1/20 0.40
RCE1 Q9Y256 1/20 0.40
RAB9A P51151 3/20 0.39
HDAC6 Q9UBN7 2/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10738515 0.88 MEN1 (0.60) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL9340133 0.87 SMN1; SMN2 (0.61) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL8795261 0.84 MDH1 (0.51) SMN1; SMN2MAPK1ALDH1A1MAPTTRPV1
SCHEMBL10601000 0.82 MEN1 (0.54) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL11703999 0.82 ALDH1A1 (0.56) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL10525796 0.82 SMN1; SMN2 (0.56) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL10602285 0.82 SMN1; SMN2 (0.53) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL7063221 0.81 SMN1; SMN2 (0.55) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL8108006 0.81 MEN1 (0.57) NPSR1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL8622770 0.81 NPSR1 (0.42) NPSR1SMN1; SMN2MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903350-B1 Pyrrolotriazole derivative FUJI PHOTO FILM CO LTD (JP) 2003-03-12 EP disclosed
US-6001551-A CONTAINING A CYAN COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1999-12-14 US disclosed
EP-0569979-B1 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-10-06 EP disclosed
EP-0703210-B1 Process for producing 2,6-di-tert-alkylcyclohexanol FUJI PHOTO FILM CO LTD (JP) 1999-03-31 EP disclosed
EP-0903350-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1999-03-24 EP disclosed
EP-0573008-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1998-11-18 EP disclosed
US-5639590-A PYRROLOAZOLE-TYPE CYAN COUPLER AND HIGH BOILING SOLVENT ON SUPPORT FUJI PHOTO FILM CO., LTD. (JP) 1997-06-17 US disclosed
US-5547825-A INCLUDES ON THE SUPPORT THE COMBINATION OF A PYRROLOAZOLE TYPE CYAN COUPLER AND A REDOX COMPOUND HAVING A MOLECULAR WEIGHT OF AT LEAST 350; LIGHT FAST REPRODUCTIONS UNDER HIGH AND LOW HUMIDITY FUJI PHOTO FILM CO., LTD. (JP) 1996-08-20 US disclosed
US-5543282-A COLORFASTNESS, STABILITY, FUJI PHOTO FILM CO., LTD. (JP) 1996-08-06 US disclosed
US-5508421-A Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye FUJI PHOTO FILM CO., LTD. (JP) 1996-04-16 US disclosed
US-5415982-A Pyrroloazoletype cyan coupler, scarcely water soluble epoxy compound FUJI PHOTO FILM CO., LTD. (JP) 1995-05-16 US disclosed
US-5370978-A Reduction of stain generation in white area on storage FUJI PHOTO FILM CO., LTD. (JP) 1994-12-06 US disclosed
US-5362882-A Intermediates for dyes for polyesters, images for heat sensitive elements and electrography FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US disclosed
EP-0574948-A1 Silver halide color photographic photosensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1993-12-22 EP disclosed
EP-0573008-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-12-08 EP disclosed
EP-0569979-A1 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-11-18 EP disclosed
EP-0518238-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1992-12-16 EP disclosed
US-4171975-A MAGENTA COUPLER AND AN AMIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-10-23 US disclosed
US-4108663-A MULTILAYER FUJI PHOTO FILM CO., LTD. (JP) 1978-08-22 US disclosed
US-4052213-A OXAZOLINONE-2-COMPOUNDS CONTAINING A MERCAPTO GROUP AGFA-GEVAERT, A.G. (DT) 1977-10-04 US disclosed