SCHEMBL81081

SCHEMBL81081

COc1ccc(Cn2sccc2=O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
ALOX15 P16050 3/20 0.62
MAPT P10636 3/20 0.62
G6PD P11413 2/20 0.62
HPGD P15428 2/20 0.62
HSD17B10 Q99714 2/20 0.62
PKM P14618 1/20 0.62
HTT P42858 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
CMA1 P23946 1/20 0.54
GSK3A P49840 2/20 0.51
GSK3B P49841 2/20 0.51
CASP3 P42574 2/20 0.51
TP53 P04637 1/20 0.46
HSP90AA1 P07900 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
HIF1A Q16665 1/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9322109 0.81 ALDH1A1 (0.68) ALDH1A1ALOX15MAPTG6PDHPGD
SCHEMBL5593583 0.77 ALDH1A1 (0.68) ALDH1A1ALOX15MAPTG6PDHPGD
SCHEMBL5593578 0.75 HSD17B10 (0.60) ALDH1A1ALOX15MAPTG6PDHPGD
Hydrochloric Acid SCHEMBL9320078 0.75 ALDH1A1 (0.96) ALDH1A1ALOX15MAPTG6PDHPGD
Hydrochloric Acid SCHEMBL11708755 0.74 ALDH1A1 (0.93) ALDH1A1ALOX15MAPTG6PDHPGD
SCHEMBL5917427 0.73 ALDH1A1 (0.67) ALDH1A1ALOX15MAPTG6PDHPGD
SCHEMBL9132212 0.71
SCHEMBL5593792 0.70 ALDH1A1 (0.71) ALDH1A1ALOX15MAPTG6PDHPGD
SCHEMBL3655957 0.70 ALDH1A1 (0.57) ALDH1A1ALOX15MAPTG6PDHPGD
SCHEMBL5593827 0.70 ALDH1A1 (0.57) ALDH1A1ALOX15MAPTG6PDHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US claimed
US-20160290036-A1 HEAT-SHIELDING MATERIAL AND WINDOW GLASS FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20090087552-A1 METHOD OF PRODUCING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2042334-A2 Method of producing heat-sensitive transfer image-receiving sheet Fujifilm Corporation (JP) 2009-04-01 EP disclosed
US-20090011154-A1 THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US disclosed
EP-0331319-B1 Method for the formation of images KONISHIROKU PHOTO IND (JP) 1994-01-26 EP disclosed
US-H1090-H High contrast; hydrazide, isothizolone, bromonitroalcohol KONICA CORPORATION (JP) 1992-08-04 US disclosed
US-4325201-A BACTERICIDES, FUNGICIDES, PESTICIDES, AND SLIMICIDES; PAINTS; PRESERVATIVES ROHM AND HAAS COMPANY (US) 1982-04-20 US disclosed
US-4322475-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1982-03-30 US disclosed
US-4279762-A Cutting oils containing 3-isothiazolones as biocides ROHM AND HAAS COMPANY (US) 1981-07-21 US disclosed
US-4265899-A FUNGICIDES, BACTERICIDES ROHM AND HAAS COMPANY (US) 1981-05-05 US disclosed
US-4252694-A MICROBIOCIDES ROHM AND HAAS COMPANY (US) 1981-02-24 US disclosed
US-4243403-A BACTERICIDES, ACRYLIC POLYMERS, FUNGICIDES ROHM AND HAAS COMPANY (US) 1981-01-06 US disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4105431-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1978-08-08 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed