Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124710 | 0.80 | KDM4E (0.35) | RHEBKDM4EGMNNLMNAMAPT | |
| SCHEMBL8371823 | 0.78 | KDM4E (0.55) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8626628 | 0.78 | KDM4E (0.44) | RHEBKDM4EGMNNLMNAMAPT | |
| SCHEMBL6008963 | 0.78 | KDM4E (0.55) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8367682 | 0.78 | KDM4E (0.55) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8134985 | 0.72 | KDM4E (0.44) | RHEBKDM4EGMNNLMNAMAPT | |
| SCHEMBL8143290 | 0.72 | KDM4E (0.46) | RHEBKDM4EGMNNLMNAMAPT | |
| SCHEMBL8139677 | 0.69 | KDM4E (0.34) | RHEBKDM4EGMNNLMNAMAPT | |
| SCHEMBL7043130 | 0.67 | RHEB (0.54) | RHEBKDM4ELMNAMAPTBLM | |
| SCHEMBL15532111 | 0.66 | KDM4E (0.53) | KDM4EGMNNLMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994890-A2 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-04-26 | — | — | EP | disclosed |
| WO-1998056761-A2 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-12-17 | — | — | WO | disclosed |