Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859572 | 0.80 | MAPT (0.59) | MAPTALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL5654152 | 0.79 | MAPT (1.00) | MAPTALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL10522322 | 0.75 | MAPT (0.66) | MAPTALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL18459148 | 0.75 | IDO1 (0.59) | MAPTALDH1A1IDO1LMNAL3MBTL1 | |
| SCHEMBL8062310 | 0.74 | IDO1 (0.63) | MAPTALDH1A1IDO1AKR1C3POLB | |
| SCHEMBL8187272 | 0.72 | MAPT (0.59) | MAPTALDH1A1HTTL3MBTL1EGFR | |
| SCHEMBL13067231 | 0.71 | MAPT (0.82) | MAPTALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL10517534 | 0.70 | MAPT (0.58) | MAPTALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL10517551 | 0.70 | MAPT (0.62) | MAPTALDH1A1HTTLMNAHPGD | |
| SCHEMBL293415 | 0.69 | IDO1 (0.66) | MAPTALDH1A1HTTIDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |