Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522322 | 0.92 | MAPT (0.66) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10517534 | 0.85 | MAPT (0.58) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10514945 | 0.84 | MAPT (0.57) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10517934 | 0.83 | MAPT (0.67) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10515414 | 0.82 | MAPT (0.54) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL13067231 | 0.81 | MAPT (0.82) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10516456 | 0.79 | ALDH1A1 (0.49) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10517135 | 0.79 | MAPT (0.61) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10522672 | 0.78 | MAPT (0.54) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10516574 | 0.78 | MAPT (0.50) | MAPTALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302312-A2 | Aryloxy (or thio)-aminopyrimidines | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |