Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108507 | 0.68 | KMT2A (0.38) | KMT2AATM | |
| SCHEMBL8108408 | 0.67 | MEN1 (0.34) | KMT2A | |
| SCHEMBL8102651 | 0.67 | TSHR (0.36) | KMT2A | |
| SCHEMBL18106803 | 0.60 | L3MBTL1 (0.43) | KMT2A | |
| SCHEMBL28928733 | 0.58 | MEN1 (0.37) | KMT2A | |
| SCHEMBL3553474 | 0.56 | KMT2A (0.47) | KMT2AATM | |
| SCHEMBL783054 | 0.55 | CHRM2 (0.46) | KMT2A | |
| SCHEMBL22728348 | 0.55 | KMT2A (0.50) | KMT2AATM | |
| SCHEMBL15438497 | 0.55 | KMT2A (0.42) | KMT2AATM | |
| SCHEMBL5010489 | 0.53 | KMT2A (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071899-A | Azetidinone derivatives for the treatment of atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-06-06 | — | — | US | claimed |
| WO-1996013484-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-09 | — | — | WO | claimed |
| US-6071899-A | Azetidinone derivatives for the treatment of atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-06-06 | — | — | US | disclosed |
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013484-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-09 | — | — | WO | disclosed |