SCHEMBL8108906

SCHEMBL8108906

Cc1ccc(C)c(-c2cc(C(=O)O)ccc2C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 1/20 0.50
ALDH1A1 P00352 4/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
HPGD P15428 1/20 0.46
MYC P01106 1/20 0.45
CSNK2A1 P68400 2/20 0.44
GRIK1 P39086 1/20 0.44
GRIA1 P42261 1/20 0.44
GRIA2 P42262 1/20 0.44
GRIA3 P42263 1/20 0.44
GRIA4 P48058 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA9 Q16790 1/20 0.44
SRD5A2 P31213 1/20 0.43
RARB P10826 1/20 0.43
RARG P13631 1/20 0.43
RXRA P19793 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1646864 0.93 MYC (0.50) ALDH1A1SMN1; SMN2KMT2AMEN1MYC
SCHEMBL10783891 0.85 CSNK2A1 (0.50) ALDH1A1SMN1; SMN2MYCCSNK2A1CA12
SCHEMBL8673355 0.84 CSNK2A1 (0.59) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL7633476 0.82 KDM4E (0.55) KMT2AMYCCA12CA1CA9
SCHEMBL29370227 0.82 KDM4E (0.55) KMT2AMYCCA12CA1CA9
SCHEMBL29699465 0.82 KDM4E (0.55) KMT2AMYCCA12CA1CA9
SCHEMBL629880 0.81 MYC (0.54) ALDH1A1KMT2AMEN1MYCTSHR
SCHEMBL11154359 0.79 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL9423281 0.79 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL29064695 0.79 MYC (0.56) ALDH1A1KMT2AMEN1HPGDMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6011133-A Laminates of glass or metal and poly(alkylene dicarboxylates) and syntheses thereof BAYLOR UNIVERSITY (US) 2000-01-04 US disclosed
US-5837381-A MULTILAYER PROTECTIVE COATING; WEAR AND CORROSION RESISTANCE UNIV BAYLOR (US) 1998-11-17 US disclosed
US-5668224-A TETRAALKYL- OR TRIALKYLAMMONIUM END GROUPS BAYLOR UNIVERSITY 1997-09-16 US disclosed
US-5451643-A PROTECTIVE COATINGS FOR METALS OR GLASS BAYLOR UNIVERSITY (US) 1995-09-19 US disclosed
WO-1994020296-A1 POLY (ALKYLENE DICARBOXYLATES) AND SYNTHESES THEREOF BAYLOR UNIVERSITY (US) 1994-09-15 WO disclosed