⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559682 | 0.91 | ALDH1A1 (0.33) | — | |
| SCHEMBL27581643 | 0.91 | — | — | |
| SCHEMBL27581628 | 0.91 | ALDH1A1 (0.33) | — | |
| SCHEMBL11384375 | 0.71 | — | — | |
| SCHEMBL8823415 | 0.69 | — | — | |
| SCHEMBL306322 | 0.67 | — | — | |
| SCHEMBL3138658 | 0.63 | ALDH1A1 (0.35) | — | |
| Iodide SCHEMBL9540028 | 0.63 | — | — | |
| SCHEMBL28332646 | 0.60 | — | — | |
| Ether SCHEMBL21406 | 0.59 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024051852-A1 | PYRIMIDINE-CONTAINING POLYCYCLIC BIOLOGICAL INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-03-14 | — | — | WO | claimed |
| CN-116354901-A | Thiazolidinedione compound and preparation method and application thereof | 郑州大学 | 2023-06-30 | — | — | CN | claimed |
| CN-112870434-B | Bactericidal/bacteriostatic bioactive interface material and preparation method thereof | 江苏大学 | 2023-03-24 | — | — | CN | claimed |
| CN-114835938-A | Polyester film base for medical dry film and preparation method thereof | 乐凯医疗科技有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-112870434-A | Bactericidal/bacteriostatic bioactive interface material and preparation method thereof | 江苏大学 | 2021-06-01 | — | — | CN | claimed |
| CN-109957092-A | A kind of no-solvent polyurethane intermediate layer resin and preparation method thereof and its application in sports play shoes leather | 合肥安利聚氨酯新材料有限公司 | 2019-07-02 | — | — | CN | claimed |
| CN-108117082-A | A kind of siloxanes toughening modifying SiO2Aeroge and preparation method thereof | 武汉理工大学 | 2018-06-05 | — | — | CN | claimed |
| CN-107986674-A | A kind of alkali-free quick-coagulant | 云南森博混凝土外加剂有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-104250314-B | Viscosity metallocene PE synthesis technique in the high chlorination of water phase suspension | 江苏煦和新材料有限公司 | 2017-11-14 | — | — | CN | claimed |
| EP-2531497-B1 | Manufacture of epoxyethyl ethers or glycidyl ethers | HEXION RES BELGIUM SA (BE) | 2016-09-07 | — | — | EP | claimed |
| EP-2459559-A1 | CONDENSED PYRIDINE DERIVATIVES USEFUL AS POTENT INHIBITORS OF THE PROTEIN KINASE CK2 | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2012-06-06 | — | — | EP | claimed |
| WO-2011013002-A1 | CONDENSED PYRIDINE DERIVATIVES USEFUL AS POTENT INHIBITORS OF THE PROTEIN KINASE CK2 | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-02-03 | — | — | WO | claimed |
| US-20070225291-A1 | Substituted Pyrazinone Compounds for the Treatment of Inflammation | PFIZER INC. | 2007-09-27 | — | — | US | claimed |
| EP-1678164-B1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORP (US) | 2007-04-11 | — | — | EP | claimed |
| EP-1678146-A1 | PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| EP-1678164-A1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005040133-A1 | PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-05-06 | — | — | WO | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| WO-2005035527-A1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-21 | — | — | WO | claimed |