Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111117 | 0.98 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL8111247 | 0.96 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8096144 | 0.95 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8110959 | 0.94 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8105109 | 0.93 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8103657 | 0.91 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL8105075 | 0.90 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL8111220 | 0.90 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8105588 | 0.90 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9528879 | 0.90 | AGTR1 (0.67) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3098772-B2 | — | — | 2000-10-16 | — | — | JP | claimed |
| EP-0527851-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-02-24 | — | — | EP | claimed |
| WO-1991017148-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | claimed |
| EP-0527851-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991017148-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | disclosed |