Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 16/20 | 0.58 |
| ▸ | MAOA | P21397 | 14/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703728 | 0.83 | MAOB (0.58) | CA9MAOBMAOAAOC3EIF2AK2 | |
| SCHEMBL29724095 | 0.83 | MAOB (0.58) | CA9MAOBMAOAAOC3EIF2AK2 | |
| SCHEMBL18850317 | 0.83 | MAOB (0.58) | CA9MAOBMAOAAOC3EIF2AK2 | |
| SCHEMBL15387034 | 0.83 | MAOB (0.58) | CA9MAOBMAOAAOC3EIF2AK2 | |
| SCHEMBL2842062 | 0.80 | MAOB (0.80) | MAOBMAOA | |
| SCHEMBL1207052 | 0.79 | MAOB (0.66) | MAOBMAOAAOC3 | |
| SCHEMBL9379063 | 0.79 | MAOB (0.58) | CA9MAOBMAOAAOC3EIF2AK2 | |
| SCHEMBL29754335 | 0.79 | MAOB (0.55) | CA9MAOBMAOAAOC3EIF2AK2 | |
| SCHEMBL20715207 | 0.79 | MAOB (0.55) | CA9MAOBMAOAEIF2AK2 | |
| SCHEMBL28778453 | 0.79 | MAOB (0.55) | CA9MAOBMAOAAOC3EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |