Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.55 |
| ▸ | MAOA | P21397 | 14/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778453 | 1.00 | MAOB (0.55) | MAOBMAOACA9EIF2AK2AOC3 | |
| SCHEMBL17785603 | 0.84 | KIF11 (0.57) | MAOBMAOACA9EIF2AK2AOC3 | |
| SCHEMBL20715212 | 0.82 | MAOB (0.50) | MAOBMAOACA9AOC3 | |
| SCHEMBL29724095 | 0.82 | MAOB (0.58) | MAOBMAOACA9EIF2AK2AOC3 | |
| SCHEMBL703728 | 0.82 | MAOB (0.58) | MAOBMAOACA9EIF2AK2AOC3 | |
| SCHEMBL14764579 | 0.80 | MAOB (0.51) | MAOBMAOACA9EIF2AK2AOC3 | |
| SCHEMBL22052984 | 0.79 | MAOB (0.49) | MAOBMAOAAOC3 | |
| SCHEMBL20715626 | 0.79 | MAOB (0.49) | MAOBMAOA | |
| SCHEMBL8109567 | 0.79 | CA9 (0.62) | MAOBMAOACA9EIF2AK2AOC3 | |
| SCHEMBL18850317 | 0.79 | MAOB (0.58) | MAOBMAOACA9EIF2AK2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436955-B | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-114436955-A | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2022-05-06 | — | — | CN | disclosed |