Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8958474 | 0.99 | SIGMAR1 (0.41) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8109894 | 0.91 | SIGMAR1 (0.40) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL27350490 | 0.90 | SIGMAR1 (0.40) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8110591 | 0.87 | SIGMAR1 (0.37) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8109070 | 0.87 | SIGMAR1 (0.37) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL9437695 | 0.87 | SIGMAR1 (0.37) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL8958874 | 0.86 | BLM (0.37) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL8958468 | 0.86 | BLM (0.37) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8958234 | 0.85 | SIGMAR1 (0.58) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8116418 | 0.85 | SIGMAR1 (0.58) | SIGMAR1TP53CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673933-B1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR (FR) | 2000-11-08 | — | — | EP | disclosed |
| EP-0673933-A1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |