Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | FABP3 | P05413 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28487041 | 0.93 | KMT2A (0.46) | KMT2AALDH1A1PTK2BMAPK1MEN1 | |
| SCHEMBL9774307 | 0.92 | KMT2A (0.51) | KMT2AALDH1A1PTK2BMAPK1MEN1 | |
| SCHEMBL13607844 | 0.90 | HTT (0.53) | KMT2AALDH1A1PTK2BMAPK1CNR2 | |
| SCHEMBL8080660 | 0.90 | MEN1 (0.57) | KMT2AMEN1CNR1CNR2LMNA | |
| SCHEMBL28423414 | 0.90 | KMT2A (0.53) | KMT2AALDH1A1PTK2BMAPK1MEN1 | |
| SCHEMBL8081846 | 0.89 | LMNA (0.60) | KMT2AALDH1A1MEN1CNR1CNR2 | |
| SCHEMBL8081832 | 0.89 | LMNA (0.60) | KMT2AALDH1A1MEN1CNR1CNR2 | |
| SCHEMBL9417688 | 0.89 | LMNA (0.60) | KMT2AALDH1A1MEN1CNR1CNR2 | |
| SCHEMBL8085142 | 0.89 | LMNA (0.60) | KMT2AALDH1A1MEN1CNR1CNR2 | |
| SCHEMBL8086789 | 0.89 | LMNA (0.60) | KMT2AALDH1A1MEN1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113062-A1 | PDIA4 INHIBITORS AND USE THEREOF FOR INHIBITING ß-CELL PATHOGENESIS AND TREATING DIABETES | ACADEMIA SINICA (CN) | 2021-06-10 | — | — | WO | disclosed |
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
| EP-0507576-A1 | Polypropylene-based resin compositions | TOSOH CORPORATION (JP) | 1992-10-07 | — | — | EP | disclosed |