SCHEMBL8109910

SCHEMBL8109910

COc1ccc([C@@H](CCCN)N2Cc3c(cccc3N3CCN(C(=O)OC(C)(C)C)CC3)C2=O)cc1OC

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 19/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2343966 0.86 UTS2R (0.71) UTS2R
SCHEMBL2585279 0.86 UTS2R (0.69) UTS2R
SCHEMBL8234408 0.85 UTS2R (0.70) UTS2R
SCHEMBL12174289 0.85 UTS2R (0.58) UTS2R
SCHEMBL12174287 0.84 UTS2R (0.79) UTS2R
SCHEMBL12174290 0.83 UTS2R (0.82) UTS2R
SCHEMBL2346366 0.83 UTS2R (0.74) UTS2R
SCHEMBL2579621 0.82 UTS2R (0.67) UTS2R
SCHEMBL12455636 0.82 UTS2R (0.63) UTS2R
SCHEMBL8101792 0.82 UTS2R (0.60) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008153902-A2 UROTENSIN II RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA, N.V. (BE) 2008-12-18 WO disclosed