SCHEMBL8101792

SCHEMBL8101792

COc1ccc([C@@H](CCCNS(=O)(=O)C2CC=CS2)N2Cc3c(cccc3N3CCN(C(=O)OC(C)(C)C)CC3)C2=O)cc1OC

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12456273 0.89 UTS2R (0.73) UTS2R
SCHEMBL8111153 0.89 UTS2R (0.60) UTS2R
SCHEMBL12174287 0.86 UTS2R (0.79) UTS2R
SCHEMBL8109910 0.82 UTS2R (0.57) UTS2R
SCHEMBL12157538 0.81 UTS2R (0.71) UTS2R
SCHEMBL12174289 0.79 UTS2R (0.58) UTS2R
SCHEMBL12174290 0.79 UTS2R (0.82) UTS2R
SCHEMBL12455636 0.78 UTS2R (0.63) UTS2R
SCHEMBL8117296 0.77 UTS2R (0.74) UTS2R
SCHEMBL8115652 0.76 UTS2R (0.75) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008153902-A2 UROTENSIN II RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA, N.V. (BE) 2008-12-18 WO disclosed