Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224391 | 0.84 | KMT2A (0.55) | CXCR3EBPSIGMAR1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6030424 | 0.83 | KMT2A (0.54) | CXCR3EBPSIGMAR1NPC1RAB9A | |
| Bromide SCHEMBL8915312 | 0.83 | KMT2A (0.54) | CXCR3EBPSIGMAR1NPC1RAB9A | |
| SCHEMBL5244816 | 0.83 | EBP (0.58) | CXCR3EBPSIGMAR1NPC1RAB9A | |
| Bromide SCHEMBL9774783 | 0.82 | KMT2A (0.52) | CXCR3EBPSIGMAR1NPC1RAB9A | |
| SCHEMBL9774969 | 0.79 | CXCR3 (0.47) | CXCR3EBPSIGMAR1NPC1RAB9A | |
| SCHEMBL8274718 | 0.79 | KMT2A (0.49) | CXCR3EBPSIGMAR1NPC1RAB9A | |
| SCHEMBL5247026 | 0.78 | EBP (0.62) | CXCR3EBPSIGMAR1NPC1RAB9A | |
| SCHEMBL9774792 | 0.77 | EBP (0.45) | CXCR3EBPSIGMAR1NPC1RAB9A | |
| SCHEMBL31194842 | 0.76 | KCNH2 (0.54) | CXCR3EBPSIGMAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705816-B1 | BENZENE DERIVATIVE USEFUL FOR ISCHEMIC DISEASES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2000-09-20 | — | — | EP | claimed |
| US-5998452-A | CARDIOVASCULAR DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-12-07 | — | — | US | claimed |
| EP-0705816-A1 | BENZENE DERIVATIVE USEFUL FOR ISCHEMIC DISEASES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1996-04-10 | — | — | EP | claimed |