Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.55 |
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120404 | 0.95 | ANPEP (0.63) | ANPEPDPP8DPP7DPP4DPP9 | |
| SCHEMBL30905445 | 0.92 | ANPEP (0.58) | ANPEPDPP8DPP7DPP4DPP9 | |
| Hydrochloric Acid SCHEMBL17133759 | 0.91 | ANPEP (0.67) | ANPEPDPP8DPP7DPP4DPP9 | |
| Trifluoroacetic Acid SCHEMBL30905260 | 0.87 | ANPEP (0.52) | ANPEPDPP8DPP7DPP4DPP9 | |
| SCHEMBL7321298 | 0.84 | ANPEP (0.71) | ANPEPDPP8DPP7DPP4DPP9 | |
| SCHEMBL12668303 | 0.84 | ANPEP (0.61) | ANPEPDPP8DPP7DPP4DPP9 | |
| SCHEMBL2037306 | 0.83 | SLC1A3 (0.70) | ANPEPDPP8DPP7DPP4DPP9 | |
| SCHEMBL2677967 | 0.83 | SLC1A3 (0.70) | ANPEPDPP8DPP7DPP4DPP9 | |
| SCHEMBL4986552 | 0.83 | SLC1A3 (0.70) | ANPEPDPP8DPP7DPP4DPP9 | |
| SCHEMBL9656664 | 0.83 | DPP8 (0.64) | ANPEPDPP8DPP7DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |