Sugi Predict

Sugi Predict / Compounds / SCHEMBL2037306

SCHEMBL2037306

SCHEMBL2037306

NC(CCCNC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SLC1A3 P43003 1/20 0.70
▸ SLC1A1 P43005 1/20 0.70
▸ DPP8 Q6V1X1 3/20 0.64
▸ DPP7 Q9UHL4 3/20 0.64
▸ HTT P42858 1/20 0.63
▸ ANPEP P15144 1/20 0.61
▸ DPP4 P27487 2/20 0.59
▸ DPP9 Q86TI2 2/20 0.59
▸ LMNA P02545 1/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.58
▸ FOLH1 Q04609 5/20 0.57
▸ TGM2 P21980 1/20 0.56
▸ KEAP1 Q14145 2/20 0.55
▸ NFE2L2 Q16236 2/20 0.55
▸ MMP2 P08253 1/20 0.54
▸ MMP9 P14780 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2677967 1.00 SLC1A3 (0.70) SLC1A3SLC1A1DPP8DPP7HTT
SCHEMBL4986552 1.00 SLC1A3 (0.70) SLC1A3SLC1A1DPP8DPP7HTT
Hydrochloric Acid SCHEMBL5652476 0.99 SLC1A3 (0.69) SLC1A3SLC1A1DPP8DPP7HTT
Hydrochloric Acid SCHEMBL29025567 0.99 SLC1A3 (0.69) SLC1A3SLC1A1DPP8DPP7HTT
Hydrochloric Acid SCHEMBL6751263 0.99 SLC1A3 (0.69) SLC1A3SLC1A1DPP8DPP7HTT
SCHEMBL453671 0.96 DPP8 (0.69) SLC1A3SLC1A1DPP8DPP7HTT
SCHEMBL5816135 0.96 DPP8 (0.69) SLC1A3SLC1A1DPP8DPP7HTT
SCHEMBL464672 0.96 DPP8 (0.69) SLC1A3SLC1A1DPP8DPP7HTT
Hydrochloric Acid SCHEMBL18770783 0.95 DPP8 (0.68) SLC1A3SLC1A1DPP8DPP7HTT
Hydrochloric Acid SCHEMBL7297967 0.95 DPP8 (0.68) SLC1A3SLC1A1DPP8DPP7HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3584277-B1 ANTIMICROBIAL SILICONE RUBBER, PREPARATION METHOD THEREFOR AND USE THEREOF SUZHOU DOBIOM MEDICAL TECH CO LTD (CN) 2022-06-29 — — EP claimed
US-11001688-B2 Antimicrobial silicone rubber, preparation method therefor and use thereof Suzhou DOBION Medical Technology Co., Ltd. (CN) 2021-05-11 — — US claimed
US-20230381146-A1 SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF HELIOS HUAMING BIOPHARMA CO., LTD. (CN) 2023-11-30 — — US disclosed
CN-116367832-A Substituted heteroaryl compounds and uses thereof 苏州华明道康生物医药有限公司 2023-06-30 — — CN disclosed
US-11655210-B2 Compound for improving L-arginine bioavailability THE GENERAL HOSPITAL CORPORATION (US) 2023-05-23 — — US disclosed
US-11655210-B2 Compound for improving L-arginine bioavailability THE GENERAL HOSPITAL CORPORATION (US) 2023-05-23 — — US disclosed
US-20230034201-A1 Formation of N-Protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2023-02-02 — — US disclosed
CN-115475229-A Preparation and use of active oxygen scavenger 凯瑞康宁生物工程（武汉）有限公司 2022-12-16 — — CN disclosed
CN-111356699-B Preparation and use of active oxygen scavenger 凯瑞康宁生物工程（武汉）有限公司 2022-08-23 — — CN disclosed
EP-3584277-B1 ANTIMICROBIAL SILICONE RUBBER, PREPARATION METHOD THEREFOR AND USE THEREOF SUZHOU DOBIOM MEDICAL TECH CO LTD (CN) 2022-06-29 — — EP disclosed
US-20210206717-A1 Compound for Improving L-Arginine Bioavailability THE GENERAL HOSPITAL CORPORATION 2021-07-08 — — US disclosed
WO-2009105824-A1 METHODS OF MODULATING THE ACTIVITY OF THE MC5 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR MIMETICA PTY LTD (AU) 2009-09-03 — — WO disclosed
WO-2009105823-A1 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS MIMETICA PTY LTD (AU) 2009-09-03 — — WO disclosed
US-20090221557-A1 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS Marp Therapeutics Pty Ltd (AU) 2009-09-03 — — US disclosed
CN-1898227-A As prostaglandin E2Ornithine derivatives as agonists or antagonists ASTELLAS PHARMA INC (JP) 2007-01-17 — — CN disclosed
EP-0680469-B1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME BOEHRINGER INGELHEIM PHARMA (DE) 2000-04-26 — — EP disclosed
EP-0446699-A1 Inhibitors of nitric oxide biosynthesis MERRELL PHARMACEUTICALS INC. (US) 1991-09-18 — — EP disclosed
US-4560795-A α-Halomethyl derivatives of α-amino acids Merrell Dow France et Cie. (FR) 1985-12-24 — — US disclosed
US-4496588-A HALOMETHYL DERIVATIVES OF A-AMINO ACID MERRELL TORAUDE ET COMPAGNIE (FR) 1985-01-29 — — US disclosed
US-4438270-A DECARBOXYLASE INHIBITORS MERRELL TORAUDE ET COMPAGNIE (FR) 1984-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230034201-A1 Formation of N-Protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine PGM2, DNPEP, NPEPPS SLC1A3 1627/4885SLC1A1 1633/4885DPP8 231/4885
US-20230381146-A1 SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF SSB, BTK, PADI6 SLC1A3 1869/4885SLC1A1 2089/4885DPP8 9/4885
US-20090221557-A1 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS MC5R, MC1R, MC3R SLC1A3 1500/4885SLC1A1 1233/4885DPP8 1646/4885
US-20210206717-A1 Compound for Improving L-Arginine Bioavailability ARG1, ARG2, NOS2 SLC1A3 128/4885SLC1A1 250/4885DPP8 519/4885
US-11655210-B2 Compound for improving L-arginine bioavailability ARG1, ARG2, NOS2 SLC1A3 128/4885SLC1A1 250/4885DPP8 519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.