Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.30 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495814 | 1.00 | SPHK1 (0.35) | SPHK1HCRTR2ATMCAPN9CAPN1 | |
| SCHEMBL8145278 | 1.00 | SPHK1 (0.35) | SPHK1HCRTR2ATMCAPN9CAPN1 | |
| SCHEMBL8112146 | 1.00 | SPHK1 (0.35) | SPHK1HCRTR2ATMCAPN9CAPN1 | |
| SCHEMBL14750633 | 0.87 | SPHK1 (0.38) | SPHK1HCRTR2 | |
| SCHEMBL5496374 | 0.86 | SPHK1 (0.34) | SPHK1HCRTR2 | |
| SCHEMBL5849654 | 0.84 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL7321665 | 0.82 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL7284303 | 0.82 | SPHK1 (0.34) | SPHK1HCRTR2 | |
| SCHEMBL8919455 | 0.82 | SPHK1 (0.44) | SPHK1 | |
| SCHEMBL7288124 | 0.81 | SPHK1 (0.34) | SPHK1HCRTR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862563-B1 | 10-DEACETYL-14BETA-HYDROXYBACCATINE III DERIVATIVES, A PROCESS FOR THE PREPARATION THEREOF AND FORMULATIONS CONTAINING THEM | INDENA SPA (IT) | 2000-08-09 | — | — | EP | disclosed |