Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113566 | 0.97 | HDAC3 (0.45) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC3 | |
| SCHEMBL8119426 | 0.96 | HDAC3 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC3 | |
| SCHEMBL8112110 | 0.90 | HDAC3 (0.41) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC3 | |
| SCHEMBL4650760 | 0.89 | TRPV1 (0.41) | TRPV1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL8119497 | 0.87 | HDAC3 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC3 | |
| SCHEMBL8119963 | 0.86 | HDAC3 (0.43) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC3 | |
| SCHEMBL8114061 | 0.85 | PLAAT3 (0.41) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC3 | |
| SCHEMBL9201861 | 0.83 | TRPV1 (0.41) | TRPV1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL8122024 | 0.82 | HDAC3 (0.41) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC3 | |
| SCHEMBL1593414 | 0.82 | NPY1R (0.42) | NPY5RNPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |