Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | EPOR | P19235 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120085 | 0.94 | CNR1 (0.36) | CNR1CNR2EPOR | |
| SCHEMBL8122513 | 0.94 | HDAC3 (0.37) | CNR1CNR2EPORMME | |
| SCHEMBL8127029 | 0.94 | NPY1R (0.41) | CNR1CNR2EPOR | |
| SCHEMBL8122704 | 0.93 | TPSAB1 (0.36) | CNR1CNR2EPOR | |
| SCHEMBL8126149 | 0.93 | TDP1 (0.45) | CNR1EPOR | |
| SCHEMBL8112714 | 0.93 | MEN1 (0.42) | CNR1CNR2 | |
| SCHEMBL8113179 | 0.92 | CNR1 (0.41) | CNR1CNR2EPOR | |
| SCHEMBL8113195 | 0.92 | CNR1 (0.34) | CNR1CNR2EPORMME | |
| SCHEMBL8529383 | 0.91 | EPOR (0.38) | CNR1EPORMME | |
| SCHEMBL8128254 | 0.90 | TPSAB1 (0.38) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |