Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121075 | 0.97 | NPSR1 (0.52) | MEN1KMT2AGAAMMP1MMP3 | |
| SCHEMBL8121078 | 0.97 | NPSR1 (0.52) | MEN1KMT2AGAAMMP1MMP3 | |
| SCHEMBL20803463 | 0.84 | CNR1 (0.57) | MEN1KMT2AGAANPSR1ALDH1A1 | |
| SCHEMBL5100260 | 0.84 | CNR1 (0.57) | MEN1KMT2AGAANPSR1ALDH1A1 | |
| SCHEMBL7850315 | 0.83 | CTSK (0.62) | MEN1KMT2AGAAMMP1MMP3 | |
| SCHEMBL4438612 | 0.82 | C3AR1 (0.56) | MEN1KMT2AGAAMMP1MMP3 | |
| SCHEMBL12890796 | 0.82 | CTSK (0.65) | MEN1KMT2AGAAMMP1MMP3 | |
| SCHEMBL27793178 | 0.82 | C3AR1 (0.56) | MEN1KMT2AGAAMMP1MMP3 | |
| SCHEMBL8120861 | 0.82 | NPY1R (0.61) | CA1CA2NPY1R | |
| SCHEMBL6379515 | 0.81 | FOLH1 (0.57) | MEN1KMT2AGAAMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |