⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246913 | 0.82 | — | — | |
| SCHEMBL247364 | 0.75 | — | — | |
| SCHEMBL245894 | 0.72 | — | — | |
| SCHEMBL246348 | 0.72 | — | — | |
| SCHEMBL10635 | 0.70 | — | — | |
| SCHEMBL234312 | 0.70 | — | — | |
| SCHEMBL2487030 | 0.68 | — | — | |
| SCHEMBL201982 | 0.67 | — | — | |
| SCHEMBL6809099 | 0.67 | — | — | |
| SCHEMBL250794 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062815-A | VMAT2 inhibitors and methods of use | 纽罗克里生物科学有限公司 | 2023-11-14 | — | — | CN | claimed |
| EP-4168409-A1 | VMAT2 INHIBITORS AND METHODS OF USE | Neurocrine Biosciences, Inc. (US) | 2023-04-26 | — | — | EP | claimed |
| EP-0757081-B1 | Curable oil- and water-repellent silicone composition | DOW CORNING TORAY SILICONE (JP) | 2002-06-05 | — | — | EP | claimed |
| US-5880227-A | Curable oil-and water-repellent silicone composition | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1999-03-09 | — | — | US | claimed |
| EP-0757081-A2 | Curable oil- and water-repellent silicone composition | Dow Corning Toray Silicone Company Ltd. (JP) | 1997-02-05 | — | — | EP | claimed |
| US-5595675-A | TREATMENT OF FIBERS WITH POLYDIMETHYLSILOXANES, FATTY ACID SALT AND ORGANOPOLYSILOXANE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1997-01-21 | — | — | US | claimed |
| EP-0588105-A1 | Derivatives of Phosphoryloxypyrazole | BAYER AG (DE) | 1994-03-23 | — | — | EP | claimed |
| CN-114026155-B | Oil-in-water type organosilicon emulsion composition and use thereof | 陶氏东丽株式会社 | 2024-02-27 | — | — | CN | disclosed |
| US-20240010647-A1 | SUBSTITUTED PYRIDO[2,1-a]ISOQUINOLINES AS VMAT2 INHIBITORS | NEUROCRINE BIOSCIENCES, INC. | 2024-01-11 | — | — | US | disclosed |
| CN-117062815-A | VMAT2 inhibitors and methods of use | 纽罗克里生物科学有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-114096627-B | Aqueous coating film-forming composition for forming antifriction coating film and airbag using the same | 陶氏东丽株式会社 | 2023-09-22 | — | — | CN | disclosed |
| US-11718618-B2 | Substituted pyrido[2,1-a]isoquinolines as VMAT2 inhibitors | NEUROCRINE BIOSCIENCES, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-20230159528-A1 | VMAT2 INHIBITORS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. | 2023-05-25 | — | — | US | disclosed |
| US-5880227-A | Curable oil-and water-repellent silicone composition | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5681914-A | Curable silicone composition | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0757081-A2 | Curable oil- and water-repellent silicone composition | Dow Corning Toray Silicone Company Ltd. (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5595675-A | TREATMENT OF FIBERS WITH POLYDIMETHYLSILOXANES, FATTY ACID SALT AND ORGANOPOLYSILOXANE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0744443-A2 | Curable silicone composition | Dow Corning Toray Silicone Company Ltd. (JP) | 1996-11-27 | — | — | EP | disclosed |
| EP-0704571-A2 | Fibre treatment compositions | Dow Corning Toray Silicone Company Limited (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0588105-A1 | Derivatives of Phosphoryloxypyrazole | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |