Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120178 | 0.92 | NPY1R (0.36) | F2NPY1RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL8125838 | 0.92 | NPY1R (0.35) | F2NPY1RTMEM97SIGMAR1MAPT | |
| SCHEMBL8119576 | 0.92 | NPY1R (0.35) | F2NPY1RTMEM97SIGMAR1MAPT | |
| SCHEMBL8126826 | 0.91 | CNR1 (0.37) | F2NPY1RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL7037398 | 0.90 | MAPT (0.36) | F2NPY1RALDH1A1MAPTHTT | |
| SCHEMBL8121491 | 0.90 | TMEM97 (0.37) | F2NPY1RTMEM97SIGMAR1TDP1 | |
| SCHEMBL8119276 | 0.90 | MEN1 (0.38) | F2NPY1RMAPTHTTNPSR1 | |
| SCHEMBL8120508 | 0.89 | F2 (0.38) | F2NPY1RALDH1A1MAPTHTT | |
| SCHEMBL8124247 | 0.89 | NPY1R (0.42) | F2NPY1RNPY4R | |
| SCHEMBL8528491 | 0.89 | NPY1R (0.35) | F2NPY1RMAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |