Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 19/20 | 0.54 |
| ▸ | EDNRA | P25101 | 19/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109665 | 0.92 | EDNRB (0.48) | EDNRBEDNRAKIF11 | |
| SCHEMBL8100753 | 0.85 | EDNRB (0.49) | EDNRBEDNRA | |
| SCHEMBL8115419 | 0.74 | EDNRB (0.48) | EDNRBEDNRAKIF11 | |
| SCHEMBL9407606 | 0.73 | EDNRB (0.40) | EDNRBEDNRA | |
| SCHEMBL8113638 | 0.69 | EDNRB (0.77) | EDNRBEDNRA | |
| SCHEMBL12228356 | 0.68 | EDNRB (0.71) | EDNRBEDNRA | |
| SCHEMBL9879365 | 0.67 | EDNRB (0.48) | EDNRBEDNRA | |
| SCHEMBL8109657 | 0.65 | EDNRB (0.84) | EDNRBEDNRA | |
| SCHEMBL8109239 | 0.64 | EDNRB (0.57) | EDNRBEDNRA | |
| SCHEMBL9701160 | 0.64 | EDNRB (0.36) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0969841-A1 | USE OF CARBOXYLIC ACID DERIVATIVES FOR TREATING CANCER | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998041206-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE IN TREATING CANCER | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-24 | — | — | WO | disclosed |