Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 14/20 | 0.36 |
| ▸ | EDNRA | P25101 | 14/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407606 | 0.73 | EDNRB (0.40) | EDNRBEDNRAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9701288 | 0.70 | POLB (0.39) | EDNRBEDNRAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9702466 | 0.68 | LMNA (0.47) | EDNRBEDNRAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9367315 | 0.67 | EDNRB (0.59) | EDNRBEDNRALMNATDP1 | |
| SCHEMBL9461243 | 0.66 | KDM4E (0.48) | EDNRBEDNRAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8943529 | 0.66 | EDNRB (0.37) | EDNRBEDNRAKDM4EALDH1A1 | |
| SCHEMBL9902726 | 0.65 | CYP1A2 (0.36) | EDNRBEDNRAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8113644 | 0.64 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL9135284 | 0.64 | AKR1C3 (0.49) | EDNRBEDNRAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9297450 | 0.63 | CYP1A2 (0.33) | EDNRBEDNRAKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517215-A1 | Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same | UBE INDUSTRIES, LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |