Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.46 |
| ▸ | CHRNG | P07510 | 3/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.46 |
| ▸ | CHRND | Q07001 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | NPY4R | P50391 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121875 | 0.94 | NPY1R (0.46) | NPY1RCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL8122121 | 0.91 | HDAC1 (0.48) | NPY1RCTSLALDH1A1HPGDKMT2A | |
| SCHEMBL8123411 | 0.88 | NPY1R (0.57) | NPY1RCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL8125986 | 0.87 | NPY1R (0.60) | NPY1RCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL8119920 | 0.81 | NPY1R (0.58) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8119924 | 0.81 | NPY1R (0.58) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8124246 | 0.81 | NPY1R (0.72) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8128052 | 0.79 | CXCR3 (0.47) | ALDH1A1KMT2A | |
| SCHEMBL8127300 | 0.79 | NPY1R (0.47) | NPY1RCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL8114058 | 0.79 | NPY1R (0.53) | NPY1RGRIA1NPFFR1NPFFR2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |