Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122540 | 1.00 | KCNH2 (0.47) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL8122306 | 1.00 | KCNH2 (0.47) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL614587 | 0.93 | KCNH2 (0.39) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL614112 | 0.86 | HRH3 (0.38) | KCNH2CYP3A4 | |
| SCHEMBL3952419 | 0.81 | FFAR1 (0.53) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL5206817 | 0.81 | FFAR1 (0.53) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL8112508 | 0.81 | FFAR1 (0.53) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL8127469 | 0.81 | FFAR1 (0.53) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL482776 | 0.79 | NPSR1 (0.39) | CYP3A4 | |
| SCHEMBL4071200 | 0.79 | FFAR1 (0.58) | KCNH2FFAR1FFAR4MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |