Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114710 | 1.00 | GRM2 (0.41) | GRM2SIGMAR1ELANECTSGPRTN3 | |
| SCHEMBL8114711 | 1.00 | GRM2 (0.41) | GRM2SIGMAR1ELANECTSGPRTN3 | |
| SCHEMBL8114802 | 0.77 | PTGER4 (0.42) | GRM2POLBALDH1A1LMNAMAPT | |
| SCHEMBL8105511 | 0.77 | ALDH1A1 (0.44) | GRM2PKMKDM4EALDH1A1LMNA | |
| SCHEMBL8105500 | 0.77 | ALDH1A1 (0.44) | GRM2PKMKDM4EALDH1A1LMNA | |
| SCHEMBL8114798 | 0.77 | PTGER4 (0.42) | GRM2POLBALDH1A1LMNAMAPT | |
| SCHEMBL8114803 | 0.77 | PTGER4 (0.42) | GRM2POLBALDH1A1LMNAMAPT | |
| SCHEMBL8116171 | 0.74 | RASGRP3 (0.54) | ALDH1A1LMNAGAAMAPTRAB9A | |
| SCHEMBL8115155 | 0.74 | RASGRP3 (0.54) | ALDH1A1LMNAGAAMAPTRAB9A | |
| SCHEMBL8115151 | 0.74 | RASGRP3 (0.54) | ALDH1A1LMNAGAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605729-B1 | OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| US-5480899-A | ANTILIPEMIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |
| EP-0605729-A1 | OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1994-07-13 | — | — | EP | disclosed |