Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119338 | 0.87 | MAPT (0.38) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL4650701 | 0.86 | CNR1 (0.35) | TACR1 | |
| SCHEMBL8120102 | 0.84 | MEN1 (0.38) | MEN1KMT2AGAAALDH1A1UTS2R | |
| SCHEMBL8126609 | 0.84 | MAPT (0.38) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL8120866 | 0.84 | MAPT (0.41) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL8123228 | 0.82 | HDAC1 (0.43) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL9196210 | 0.82 | TACR1 (0.36) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL8112794 | 0.81 | F2 (0.33) | ALDH1A1 | |
| SCHEMBL1259156 | 0.80 | MEN1 (0.50) | MEN1KMT2AGAAMMP1MMP3 | |
| SCHEMBL8586561 | 0.78 | NPSR1 (0.37) | MEN1KMT2AGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |