Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114739 | 0.84 | MEN1 (0.39) | MEN1KMT2AGAAUTS2RMMP1 | |
| SCHEMBL8120866 | 0.84 | MAPT (0.41) | MEN1KMT2AGAATDP1MAPT | |
| SCHEMBL8123228 | 0.83 | HDAC1 (0.43) | MEN1KMT2ATDP1MAPTCA1 | |
| SCHEMBL8119338 | 0.82 | MAPT (0.38) | MEN1KMT2AGAATDP1MMP1 | |
| SCHEMBL8126609 | 0.81 | MAPT (0.38) | MEN1KMT2AGAATDP1MMP1 | |
| SCHEMBL8586561 | 0.79 | NPSR1 (0.37) | MEN1KMT2AGAAMMP1MMP3 | |
| SCHEMBL1259156 | 0.79 | MEN1 (0.50) | MEN1KMT2AGAATDP1MMP1 | |
| SCHEMBL8120100 | 0.78 | NPY1R (0.50) | MMP1MMP3MMP9CA1CA2 | |
| SCHEMBL8127522 | 0.78 | MEN1 (0.32) | MEN1KMT2ATDP1 | |
| SCHEMBL8528534 | 0.78 | NPY1R (0.38) | MEN1KMT2AGAAMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |