Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15763622 | 0.71 | TRIM24 (0.39) | APPBACE1BACE2LMNATSHR | |
| SCHEMBL8107786 | 0.70 | CA1 (0.30) | — | |
| SCHEMBL7783064 | 0.68 | LMNA (0.44) | LMNATSHR | |
| SCHEMBL5881035 | 0.66 | LMNA (0.38) | LMNATSHR | |
| SCHEMBL19995807 | 0.65 | TP53 (0.32) | — | |
| SCHEMBL4697737 | 0.62 | SCN1A (0.41) | LMNATSHR | |
| SCHEMBL2993610 | 0.62 | SCN1A (0.41) | LMNATSHR | |
| SCHEMBL4655278 | 0.62 | SCN1A (0.41) | LMNATSHR | |
| SCHEMBL4654056 | 0.62 | SCN1A (0.31) | — | |
| SCHEMBL181178 | 0.62 | SCN1A (0.41) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |