SCHEMBL8115239

SCHEMBL8115239

CCCS(=O)(=O)c1cccnc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.51
MAPT P10636 3/20 0.44
TP53 P04637 1/20 0.44
GLA P06280 1/20 0.44
CDK1 P06493 1/20 0.44
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.39
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rimsulfuron SCHEMBL37660 0.93 GAA (0.54) GAAMAPTTP53GLACDK1
Rimsulfuron SCHEMBL27828098 0.93 GAA (0.54) GAAMAPTTP53GLACDK1
Rimsulfuron SCHEMBL15524978 0.92 GAA (0.53) GAAMAPTTP53GLACDK1
Rimsulfuron SCHEMBL15524977 0.92 GAA (0.53) GAAMAPTTP53GLACDK1
SCHEMBL8383691 0.91 GAA (0.50) GAAMAPTTP53GLACDK1
SCHEMBL8380181 0.89 GAA (0.51) GAAMAPTTP53GLACDK1
SCHEMBL8114121 0.87 GAA (0.52) GAAMAPTTP53GLACDK1
SCHEMBL10565660 0.86 GAA (0.56) GAAMAPTTP53GLACDK1
SCHEMBL8382870 0.86 GAA (0.49) GAAMAPTTP53GLACDK1
SCHEMBL9251565 0.86 GAA (0.49) GAAMAPTTP53GLACDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451468-B2 Substituted pyridinesulfonamide compounds, herbicidal compositions containing them, and process for their production ISHIHARA SANGYO KAISHA (JP) 2000-03-08 EP claimed
EP-0273610-B1 Herbicidal pyridinesulfonylureas DU PONT (US) 1996-09-11 EP claimed
US-5102444-A Herbicidal pyridinesulfonylureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-07 US claimed
EP-0334896-A1 HERBICIDAL PYRIDINESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-04 EP claimed
WO-1989001937-A1 HERBICIDAL PYRIDINESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-03-09 WO claimed
EP-0273610-A1 Herbicidal pyridinesulfonylureas E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-06 EP claimed
WO-1988004297-A1 HERBICIDAL PYRIDINESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-06-16 WO claimed
JP-7300473-A None JP disclosed
EP-0451468-B2 Substituted pyridinesulfonamide compounds, herbicidal compositions containing them, and process for their production ISHIHARA SANGYO KAISHA (JP) 2000-03-08 EP disclosed
EP-0273610-B1 Herbicidal pyridinesulfonylureas DU PONT (US) 1996-09-11 EP disclosed
US-5512535-A PRE- AND POSTEMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-30 US disclosed
JP-H07300473-A HERBICIDAL PYRIDINESULFONYLUREAS E I DU PONT DE NEMOURS & CO 1995-11-14 JP disclosed
US-5393733-A Herbicidal pyridinesulfonylureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-02-28 US disclosed
US-5209770-A Containing pyrimidine ring E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-11 US disclosed
US-5139565-A Herbicides which are safe for corn ISHIHARA SANGYO KAISHA LTD. (JP) 1992-08-18 US disclosed
US-5102444-A Herbicidal pyridinesulfonylureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-07 US disclosed
EP-0451468-A1 Substituted pyridinesulfonamide compounds, herbicidal compositions containing them, and process for their production ISHIHARA SANGYO KAISHA, LTD. (JP) 1991-10-16 EP disclosed
WO-1989001937-A1 HERBICIDAL PYRIDINESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-03-09 WO disclosed
US-4774337-A Herbicidal pyridinesulfonylureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-27 US disclosed
EP-0273610-A1 Herbicidal pyridinesulfonylureas E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-06 EP disclosed