Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739143 | 0.94 | GAA (0.49) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10566570 | 0.94 | TSHR (0.50) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10807485 | 0.90 | GAA (0.55) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10616134 | 0.89 | GAA (0.67) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10568037 | 0.89 | ALDH1A1 (0.52) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11284918 | 0.88 | ALDH1A1 (0.43) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10808927 | 0.87 | GAA (0.56) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8115239 | 0.86 | GAA (0.51) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10564131 | 0.85 | LMNA (0.46) | GAAMAPTGLAKDM4ENPC1 | |
| SCHEMBL10566380 | 0.85 | ALDH1A1 (0.48) | GAAMAPTTP53CDK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035893-B1 | HERBICIDAL BENZENE- AND PYRIDINE-SULFONAMIDE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-21 | — | — | EP | claimed |
| EP-0035893-A2 | Herbicidal benzene- and pyridine-sulfonamide derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-16 | — | — | EP | claimed |
| US-4818277-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-04 | — | — | US | disclosed |
| US-4683091-A | Process for the nucleophilic substitution of unactivated aromatic and heteroaromatic substrates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0035893-B1 | HERBICIDAL BENZENE- AND PYRIDINE-SULFONAMIDE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-21 | — | — | EP | disclosed |