Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2442267 | 0.83 | KDM4E (0.65) | KDM4EPOLBATMMAPTKMT2A | |
| SCHEMBL10565574 | 0.83 | ADRA1A (0.52) | ADRA1AADRA1BKDM4EPOLBATM | |
| SCHEMBL29483352 | 0.83 | KDM4E (0.65) | KDM4EPOLBATMMAPTKMT2A | |
| SCHEMBL30627284 | 0.81 | KDM4E (0.68) | ADRA1AADRA1BKDM4EPOLBATM | |
| SCHEMBL28528095 | 0.81 | KDM4E (0.62) | KDM4EPOLBATMMAPTKMT2A | |
| SCHEMBL1061421 | 0.81 | ADRA1A (0.51) | ADRA1AADRA1BKDM4EPOLBATM | |
| SCHEMBL7200106 | 0.81 | KDM4E (0.68) | ADRA1AADRA1BKDM4EPOLBATM | |
| SCHEMBL4749810 | 0.80 | GAA (0.54) | ADRA1AADRA1BKDM4EPOLBMAPT | |
| SCHEMBL29663621 | 0.79 | RXFP1 (0.55) | ADRA1AADRA1BKDM4EPOLBATM | |
| SCHEMBL109178 | 0.78 | TSHR (0.50) | ADRA1AADRA1BKMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |